睡眠障碍数值评分尺度:内容有效性,心理测量验证和Purigo Nodularis中患者内有意义的变化
Sonja Ständer1, Fatoumata Fofana2, Carla Dias-Barbosa3
1University Hospital Münster, Münster, Germany.
Dermatology and therapy
|June 17, 2023
概括
睡眠障碍数值评分表 (SD NRS) 有效地测量了结节炎 (PN) 患者的睡眠问题. 这种经过验证的工具可靠地用于临床实践和研究.
科学领域:
- 皮肤病学 皮肤病学
- 心理测量 心理测量 心理测量
- 临床试验 临床试验
背景情况:
- 睡眠障碍是 prurigo nodularis (PN) 患者的常见和重要问题.
- 需要验证的患者报告结果 (PRO) 措施来量化PN的睡眠障碍.
- 睡眠障碍数值评分尺度 (SD NRS) 被评估为PN的潜在PRO.
研究的目的:
- 评估睡眠障碍数值评分表 (SD NRS) 作为PRO用于量化PN成年人的睡眠障碍.
- 评估SD NRS的可靠性,有效性和响应能力.
- 确定PN中SD NRS的有意义的患者内变化.
主要方法:
- 进行了定性访谈,以提取SD NRS的概念和认知简报.
- 对SD NRS的心理测量评估使用了PN患者第二阶段随机试验的数据.
- 使用各种PRO来评估可靠性,有效性和响应性,包括平均 (AP) NRS,AP VRS,峰值 (PP) NRS,PP VRS和DLQI.
主要成果:
- SD NRS被95%的与PN相关睡眠障碍的受访者理解得很好.
- SD NRS表现出良好的测试重复测试可靠性 (ICC:0.87对于AP VRS,0.76对于PP VRS).
- SD NRS显示与其他PRO中度至强度的相关性,并且在患者组之间有区别,表明良好的有效性和响应性. 2至4个点的下降被认为是有意义的.
结论:
- 睡眠障碍数值评分表 (SD NRS) 是一个明确,可靠和有效的PRO衡量标准.
- SD NRS可以在临床实践和研究环境中使用.
- 这个工具有助于捕捉成年人患有 Prurigo nodularis 的睡眠障碍.
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