不充分的静脉血栓塞栓症 化学预防与创伤患者内皮外带外血栓塞栓的较高静脉血栓塞栓率有关
Navpreet K Dhillon1, Tobias Muniz2, Nicole M Fierro2
1R Adams Cowley Shock Trauma Center, University of Maryland, Baltimore, Maryland.
The Journal of surgical research
|June 17, 2023
概括
较高剂量的低分子量肝素 (LMWH) 是安全的外周导管创伤患者,减少静脉血栓栓塞 (VTE) 风险,而不会增加并发症. 这支持目前针对增强VTE预防的指导方针.
科学领域:
- 创伤外科手术是什么
- 药理学 药理学是指药理学的学科.
- 关键护理医学 关键护理医学
背景情况:
- 创伤患者通常需要静脉血栓塞栓症 (VTE) 预防.
- 创伤患者的外周导管在VTE预防方面提出了独特的挑战.
- 指南建议使用较高剂量的低分子量肝素 (LMWH) 进行预防.
研究的目的:
- 为了比较创伤患者的VTE和并发症率,外周导管接受充分与不充分的VTE预防.
- 在这个患者群体中评估更高的LMWH剂量的安全性和有效性.
主要方法:
- 对113名外围导管外伤患者 (2012-2019) 的回顾性审查.
- 定义了充足的预防措施,即每天两次服用30-40毫克的埃诺沙巴林.
- 定义的不充分的预防是每天一次的未分离的氨酸或氨酸.
主要成果:
- 在9.7% (DVT) 和1.8% (PE) 的患者中发生了VTE.
- 充足的埃诺沙巴林剂量与静脉瘤和深肠瘤的发病率较低有关.
- 外周导管相关的并发症并不取决于预防的类型.
结论:
- 在外围导管外外伤患者的VTE预防中使用较高剂量的LMWH是安全的.
- 这种方法与降低VTE率有关.
- 目前的预防策略似乎对这个高风险群体有效和安全.
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