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Updated: Jul 26, 2025

In Vitro Selection of Engineered Transcriptional Repressors for Targeted Epigenetic Silencing
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一个ZC3H4,WDR82和ARS2的限制性复合体与PNUTS集成,以控制非生产性的转录

Chris Estell1, Lee Davidson1, Joshua D Eaton1

  • 1Living Systems Institute, University of Exeter, Stocker Road, Exeter, EX4 4QD, United Kingdom.

Molecular cell
|June 17, 2023
PubMed
概括

研究人员确定ZC3H4-WDR82是非编码RNA (ncRNA) 转录的抑制剂. 这种复合体与ARS2和PNUTS一起控制ncRNA终结,而U1 snRNA保护蛋白质编码基因.

关键词:
在 ARS2 中,ARS2 是普斯 (PNUTS) 是一个全年普斯 (PNUTS).的RNA聚合酶II.这就是U1 snRNA.这是WDR82的WDR82.ZC3H4ZC3H4Z ZC3H4Z ZC3H4Z ZC3H4Z ZC3H4Z ZC3H4Z ZC3H4Z ZC3H4Z ZC3H4Z ZC3H4Z ZC3H4Z ZC3H4Z ZC3H4Z ZC3H4Z ZC3H4Z ZC3H4Z ZC3H4Z在外基因组中,外基因组是外基因组.没有编码的RNA.转录终止 转录终止

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