在慢性 Ovine 功能性三腹反中,乳头肌肉的近似度
Boguslaw Gaweda1, Manikantam Gaddam2, Tomasz Jaźwiec3
1Division of Cardiothoracic Surgery, Corewell Health, Grand Rapids, Mich; Department of Cardiac Surgery, Faculty of Medicine, Clinical District Hospital No. 2, University of Rzeszow, Rzeszow, Poland.
The Journal of thoracic and cardiovascular surgery
|June 17, 2023
概括
乳头肌肉近似通过解决亚膜重塑,有效地减少了绵羊的严重功能性三管吐. 这种技术在复杂病例中显示出作为标准三形环结形术的辅助方法的前景.
科学领域:
- 心血管外科心血管外科
- 心脏解剖学 心脏解剖学
- 手术创新 在外科创新.
背景情况:
- 功能性三回 (FTR) 随着右心室 (RV) 扩张和乳头肌肉位移,对标准的三环无效整形提出了挑战.
- 亚膜重塑是FTR修复中不足最佳结果的一个关键因素.
- 解决乳头肌肉位移可能会提高手术修复效率.
研究的目的:
- 在临床前模型中,评估乳头肌肉近似在减少FTR方面的有效性.
- 为了研究亚膜干预对RV重塑和三膜功能的影响.
- 为了评估 papillary 肌肉近似的潜力,作为一个辅助三 annuloplasty.
主要方法:
- 在绵羊中,通过快速心室节奏诱导了功能性三角管吐和双心室功能障碍.
- 植入了声微观测晶体,以监测环状肌肉和乳头肌肉动态.
- 进行了乳头肌肉近似接,并顺序收集了血液动力学,声微量学和心声回声学数据.
主要成果:
- 快速节奏导致显著的RV扩张,三管环直径增加,以及严重的FTR.
- 前后部和前部部肌肉近似均显著降低了FTR严重程度 (P < .001).
- 成功的乳头肌肉近似与相对环状心肌相对较低的前乳头肌肉位移相关.
结论:
- 乳头肌肉近似有效地减少了在RV扩张和乳头肌肉位移的临床前羊模型中严重的FTR.
- 这种亚膜干预表明,对于复杂的FTR而言,它具有作为戒指解环整形手术的辅助的潜力.
- 需要进一步的研究来证实乳头肌肉近似在FTR修复中的临床实用性.
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