认知障碍发生前和发生期间的人格变化
Antonio Terracciano1, Martina Luchetti2, Yannick Stephan3
1Department of Geriatrics, Florida State University, Tallahassee, FL, USA.
Journal of the American Medical Directors Association
|June 17, 2023
概括
在认知障碍期间,人格特征发生变化,外向性,和性和良心性下降. 这些变化随着痴呆症的进展而加速,影响行为和情绪.
科学领域:
- 心理学 心理学 心理学
- 神经科学是一个神经科学.
- 老年学是一门学科.
背景情况:
- 回顾性研究表明,认知障碍或痴呆症患者的个性变化.
- 这些人格变化的确切时间和程度尚不清楚.
研究的目的:
- 在认知障碍出现之前和期间,前性地检查五大个性特征的轨迹.
- 了解个性变化如何在认知衰退的不同阶段演变.
主要方法:
- 一项纵向观察性队列研究,涉及22,611名来自健康和退休研究的老年人.
- 从2006年到2020年,参与者每四年完成一次人格评估,并进行认知障碍评估.
- 多层次建模用于分析人格变化,控制人口统计和与年龄相关的规范.
主要成果:
- 在可检测到的认知障碍之前,人们观察到外向,愉悦和良心的轻微下降.
- 在认知障碍期间,所有五种人格特征都表现出加速变化:神经病症增加,而外向,开放性,和性和良心性减少.
- 与临床前阶段相比,在认知障碍期间,人格变化速度明显更快.
结论:
- 认知障碍与临床前和临床阶段的有害人格转变有关.
- 观察到的个性变化在损伤之前太小和不一致,无法可靠地预测痴呆症的发病.
- 认知衰退期间加速的人格变化可能会导致痴呆症中出现的行为和心理症状.
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