乳腺核磁共振扫描上背景辅酶增强与乳腺癌的相关性
H Sallam1, L Lenga1, C Solbach2
1Department of Radiology, University Hospital Frankfurt, Frankfurt am Main, Germany.
Clinical radiology
|June 17, 2023
概括
乳腺MRI上的背景辅酶增强 (BPE) 似乎不是预测乳腺癌风险的可靠生物标志物. 这项研究没有发现BPE与高风险女性癌症发展之间存在显著的相关性.
科学领域:
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
- 医疗成像医学成像
背景情况:
- 乳房MRI上的背景辅酶增强 (BPE) 是一个常见的发现.
- 它在乳腺癌风险评估中的预后价值需要进一步澄清.
研究的目的:
- 评估乳腺癌风险较高的女性乳腺MRI中BPE的预后价值.
主要方法:
- 对327名高风险女性进行乳腺核磁共振和活检的回顾性横截面研究.
- 对BPE与患者年龄,纤维腺组织,BIRADS,癌症存在和受体状态 (HER2,PR,ER,Ki67) 的相关性进行分析.
主要成果:
- 在BPE和纤维腺组织和患者年龄之间观察到微弱的相关性.
- 在正确的BPE和HER2状态,以及正确的BPE和正确的BIRADS之间发现了显著的相关性.
- 在绝经前或绝经后的妇女中,没有发现BPE和乳腺癌之间的显著关联.
结论:
- 乳腺MRI上的BPE在这个高风险队列中没有显示与乳腺癌发展的显著相关性.
- BPE可能不是预测乳腺癌风险的可靠生物标志物.
- 在右乳和左乳之间没有观察到关于BPE和癌症相关性的显著差异.
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