方法比较和估计失眠对健康结果的因果作用在调查样本人口的调查
Anja Shahu1,2, Joon Chung2, Wassim Tarraf3
1Department of Biostatistics, Harvard T.H. Chan of Public Health, Boston, MA, USA.
Scientific reports
|June 17, 2023
概括
从调查数据中推断因果关系需要仔细处理调查重量和设计. 结合调查重量作为共变量的匹配方法提高了准确性,特别是与未测量的混因子,揭示失眠.
科学领域:
- 流行病学 流行病学
- 生物统计学 生物统计学
- 调查方法 调查方法
背景情况:
- 从调查数据中推断因果关系需要整合调查权重和设计,以进行代表性效应估计和准确的标准误差 (SE).
- 存在各种权重和匹配方法用于因果推理,但它们与复杂的调查数据的性能需要仔细评估.
研究的目的:
- 为了比较不同的方法,将调查权重和设计纳入权重和基于匹配的因果推理方法.
- 在处理可能与调查样本设计相关的未测量混因素时,确定最强大的方法.
主要方法:
- 进行了一项模拟研究,以评估各种因果推理方法在模型规范和未测量的混的不同场景下的性能.
- 进行比较的方法包括权重和匹配方法,调查重量和设计特征的结合方式有所不同.
- 该研究还将选定的方法应用于西班牙裔社区健康研究/拉丁裔研究 (HCHS/SOL) 数据集.
主要成果:
- 当模型被正确指定时,大多数因果推理方法的执行都充足.
- 然而,在与调查权重相关的未测量混因子存在的情况下,只有使用调查权重在因果估计和作为匹配共变量时的匹配方法保持了良好的表现.
- 对HCHS/SOL的申请表明,失眠与轻度认知障碍 (MCI) 和事件高血压之间存在因果关系.
结论:
- 为了从调查数据中推断因果关系,特别是当未测量的混因素可能与样本设计相关时,建议将调查重量作为匹配程序中的共变量,除了用于因果关系估计外.
- 失眠与美国西班牙裔/拉丁裔人口中轻度认知障碍和事件高血压风险增加有关.
- 在复杂的调查数据中,强大的方法对于有效的因果推断至关重要.
相关概念视频
02:07Blind Procedures
10.7K
Ideally, the people who observe and record the children’s behavior are unaware of who was assigned to the experimental or control group, in order to control for experimenter bias. Experimenter bias refers to the possibility that a researcher’s expectations might skew the results of the study. Remember, conducting an experiment requires a lot of planning, and the people involved in the research project have a vested interest in supporting their hypotheses. If the observers knew which...
10.7K
01:27Insomnia
111
Insomnia is a prevalent sleep disorder characterized by difficulty falling asleep, frequent awakenings during the night, and waking up too early without being able to return to sleep. People with insomnia often experience these disruptions at least three nights a week for at least one month. Chronic insomnia, which lasts for at least three months, can lead to increased anxiety, which in turn can worsen sleep difficulties, creating a cycle of sleeplessness and stress.
Multiple factors contribute...
Multiple factors contribute...
111
01:19Management of Insomnia
284
The sleep cycle, an integral part of human health, consists of several stages with distinct characteristics and functions. It begins with a transition from wakefulness to sleep, known as the light sleep phase, followed by the restorative deep sleep phase, essential for physical recovery and growth. The cycle concludes with the Rapid Eye Movement (REM) phase, characterized by high brain activity and vivid dreaming. Insomnia, a prevalent sleep disorder, involves difficulty falling asleep, staying...
284
01:53Cause and Effect
11.0K
While variables are sometimes correlated because one does cause the other, it could also be that some other factor, a confounding variable, is actually causing the systematic movement in our variables of interest. For instance, as sales in ice cream increase, so does the overall rate of crime. Is it possible that indulging in your favorite flavor of ice cream could send you on a crime spree? Or, after committing crime do you think you might decide to treat yourself to a cone?
11.0K
01:13Insufficient Sleep and Sleep Deprivation
184
Insufficient sleep refers to not getting the recommended amount of sleep for optimal functioning, even if it's just slightly less than needed. Sleep insufficiency may occur due to lifestyle choices, such as staying up late for social events or work, resulting in routinely getting less sleep than required. For example, consistently sleeping 6 hours when the body needs 7-9 hours can lead to cumulative effects on health and well-being.
Sleep deprivation is a more severe form of sleep loss...
Sleep deprivation is a more severe form of sleep loss...
184
01:28Criteria for Causality: Bradford Hill Criteria - II
386
The Bradford Hill criteria serve as guidelines for establishing causative links in epidemiological research. Beyond Strength, Consistency, Specificity, and Temporality, key criteria also include Biological Gradient, Plausibility, Coherence, Experiment, and Analogy. These principles assist scientists in assessing the likelihood of causation in complex biological contexts. Below is a summary of these concepts:
386