相关实验视频
Updated: Jul 26, 2025

08:45
Forming Giant-sized Polymersomes Using Gel-assisted Rehydration
Published on: May 26, 2016
9.4K
海星聚合体聚合物的形态发生.
Jiawei Sun1, Sandra Kleuskens1, Jiabin Luan1
1Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ, Nijmegen, the Netherlands.
Nature communications
|June 17, 2023
概括
研究人员使用响应性聚合物和盐离子控制了聚合物的形状. 这一突破允许可调节的多臂结构在纳米医学中具有潜在的应用.
科学领域:
- 聚合物科学 聚合物科学
- 材料科学是一种材料科学.
- 纳米技术 纳米技术
背景情况:
- 聚合物囊泡或聚合体为药物输送和纳米反应器等应用提供稳定性和多功能性.
- 控制聚合体的形状对于释放它们的全部潜力至关重要,但仍然是一个重大挑战.
研究的目的:
- 用响应性疏水性单元研究聚合物膜上局部曲率形成的控制.
- 探索盐离子在调节响应性聚合物的特性及其与聚合物膜相互作用中的作用.
- 制造和调整聚合体的形态,特别是创建多臂结构.
主要方法:
- 在聚合物膜中将聚烯 (N-异烯胺) 作为响应性疏水性单元的纳入.
- 通过添加盐离子来调节聚 (N-异烯胺) 特性和膜相互作用.
- 聚合体的制造和调整他们的多臂结构通过变化的盐度.
主要成果:
- 在聚合物膜上证明了对局部曲率形成的控制.
- 成功制造了多臂聚合体,其中臂数可以根据盐度调节.
- 鉴定了盐离子对聚烯 (N-异烯胺) 插入聚合物膜的热力学影响.
结论:
- 通过将响应性聚合物和盐离子结合起来,可以实现聚合体的受控形状转换.
- 该方法提供了对盐离子在合成聚合物膜和天然生物膜的曲率形成中的作用的见解.
- 响应刺激的非球形聚合体对先进的应用有前途,特别是在纳米医学中.
相关概念视频
Mechanism of Lamellipodia Formation
2.6K
Cells migrating in response to external stimuli form lamellipodia, which are thin membrane protrusions supported by a mesh of linked, branched, or unbranched actin filaments. These actin filaments interact with myosin motor proteins, creating the dynamic actomyosin complex within the cytoskeleton. Contractility, or the ability to generate contractile stress, is inherent to the actomyosin complex. It helps cells detect the stiffness of the surrounding ECM and exert contractile force for...
2.6K
Mechanism of Filopodia Formation
2.4K
Filopodia are thin, actin-rich cellular protrusions that play an important role in many fundamental cellular functions. They vary in their occurrence, length, and positioning in different cell types, suggesting their diverse roles.
Their main function is to guide migrating cells during normal tissue morphogenesis or cancer metastasis by recognizing and making initial contacts with the extracellular matrix. However, they can also act as stationary cell anchors or help to establish communication...
Their main function is to guide migrating cells during normal tissue morphogenesis or cancer metastasis by recognizing and making initial contacts with the extracellular matrix. However, they can also act as stationary cell anchors or help to establish communication...
2.4K
Molecular Weight of Step-Growth Polymers
2.2K
Step growth polymerization involves bi or multifunctional monomers. Bifunctional monomers react to form linear step growth polymers, whereas multifunctional monomers react to form non-linear or branched polymers.
As the step-growth polymerization involves step-wise condensation of monomers, the molecular weight also builds up eventually. Consequently, high molecular weight polymers are obtained at the late stages of the polymerization, where 99% of monomers have been consumed.
The extent of the...
As the step-growth polymerization involves step-wise condensation of monomers, the molecular weight also builds up eventually. Consequently, high molecular weight polymers are obtained at the late stages of the polymerization, where 99% of monomers have been consumed.
The extent of the...
2.2K
Step-Growth Polymerization: Overview
3.5K
Step-growth or condensation polymerization is a stepwise reaction of bi or multifunctional monomers to form long-chain polymers. As all the monomers are reactive, most of the monomers are consumed at the early stages of the reaction to form small chains of reactive oligomers, which then combine to form long polymer chains in the late stages. Hence, the reaction has to proceed for a long time to achieve high molecular weight polymers.
Many natural and synthetic polymers are produced by...
Many natural and synthetic polymers are produced by...
3.5K
Actin Polymerization and Cell Motility
5.3K
Actin is a family of globular proteins that are highly abundant in eukaryotic cells. It makes up approximately 1-5% of total cell protein concentration. Actin monomers polymerize to form a complex network of polarized filaments, the actin cytoskeleton, that plays a crucial role in many cellular processes, including cell motility, division, endocytosis, and metastasis of cancer cells.
Actin cytoskeleton dynamics can produce pushing, pulling, and resistance forces that help the cell to migrate....
Actin cytoskeleton dynamics can produce pushing, pulling, and resistance forces that help the cell to migrate....
5.3K
Polymers
35.9K
The word polymer is derived from the Greek words “poly” which means “many” and “mer” which means “parts”. Polymers are long chains of molecules composed of repeating units of smaller molecules, known as monomers. They either occur naturally, such as DNA and proteins, or can be constructed synthetically, like plastics. They have varied structural characteristics, such as linear chains, branched chains, or complex networks, that contribute to the...
35.9K

