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Updated: Jul 26, 2025

A Rapid and Quantitative Fluorimetric Method for Protein-Targeting Small Molecule Drug Screening
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硫尿素与正常或改性人血清白蛋白结合的表征,使用由捕获制备的亲和力微柱

Saumen Poddar1, Ashley G Woolfork1, Sazia Iftekhar1

  • 1Department of Chemistry, University of Nebraska, Lincoln, NE 68588, USA.

Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
|June 18, 2023
PubMed
概括

糖尿病诱导的蛋白质修饰,特别是人类血清白蛋白 (HSA) 中的高级糖化最终产品 (AGEs),可以改变药物结合. 这项研究使用微列来显示AGEs增加了对HSA的硫氨酸尿素药物亲和力.

关键词:
亲密关系微柱是指亲密关系微柱.药物与蛋白质结合 药物与蛋白质结合陷入陷的方法人类血清专素的人类血清专素硫烯氨酸氨基酸是什么?

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