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一个基于光谱的开源开发,用于实时IORT治疗计划系统

Sergio Lozares-Cordero¹, Carlos Bermejo-Barbanoj², Alberto Badías-Herbera³

¹Physics and Radiation Protection Department, Miguel Servet University Hospital, Zaragoza, Spain.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

|June 18, 2023

概括

这项研究引入了一种用于手术内放射治疗规划的新型光谱测量系统. 它使用实时手术部位图像来计算辐射剂量,提高软组织肉瘤治疗的精度.

科学领域:

医学物理医学物理
放射治疗技术的辐射疗法技术
手术瘤学手术瘤学

背景情况:

术内放射治疗 (IORT) 需要精确的瘤向.
传统的成像方法可能在手术室中不易获得或不是最佳的.
准确的剂量计算对于有效的IORT和最小化副作用至关重要.

研究的目的:

介绍手术内低能光子放射治疗的治疗计划系统.
用实时手术部位图像的摄像度来计算剂量.
在IORT规划中消除对计算机断层扫描的需求.

主要方法:

开发了一个使用智能手机/平板电脑图像的摄影计量系统.
该系统重建了手术部位的3D模型,用于剂量计算.
调试涉及瘤床重建的3D打印和使用放射性染色膜进行验证.

主要成果:

3D模型重建时间平均为229.6秒.
整个规划和剂量计算程序的平均时间为520.6秒.
与计算剂量相比,放射色膜测量显示出最小的差异 (1.4%-6.2%).

结论:

一个基于光谱的IORT规划系统被成功演示.
该系统可实现手术室的实时成像和规划.
验证证实了该系统对低能光子IORT的准确性.

关键词:

电子手臂疗法是一种电子手臂疗法.这里是IORTT.这是一种摄影计量技术 (photogrammetry).放射性染色膜是一种放射性染色膜.在TPS中使用TPS.

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