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Updated: Jul 26, 2025

An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
00:06

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Published on: September 12, 2019

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由于其在肝细胞癌中的致癌作用,WDR74作为一种新的治疗点

Feng Gao1, Hui Zhou2, Xiaosong Huang3

  • 1Division of Hepatobiliary and Pancreatic Surgery, Department of Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, China; NHC Key Laboratory of Combined Multi-organ Transplantation, China; Key Laboratory of the diagnosis and treatment of organ Transplantation, Research Unit of Collaborative Diagnosis and Treatment for Hepatobiliary and Pancreatic Cancer, Chinese Academy of Medical Sciences (2019RU019), China; Key Laboratory of Organ Transplantation, Research Center for Diagnosis and Treatment of Hepatobiliary Diseases, Zhejiang Province, Hangzhou 310003, China.

Pathology, research and practice
|June 18, 2023
PubMed
概括

在肝细胞癌 (HCC) 中,WD重复含有蛋白74 (WDR74) 的上调,与生存率差相关. 向WDR74可能会抑制HCC细胞增殖,并为这种耐火性癌症提供新的治疗策略.

关键词:
生物标志物生物标志物肝细胞癌是肝细胞癌.致癌作用 致癌作用这是WDR74的WDR74.

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