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Updated: Jul 26, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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来自巨细胞的IL8通过通过IL8-CXCR2轴对晚期结直肠癌患者的TIM3表达的下调来抑制CD8T细胞功能

Chenhui Zhao1, Dan Wang1, Zhen Li2

  • 1Biotherapy Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China; Cancer Center, the First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.

International immunopharmacology
|June 18, 2023
PubMed
概括

来自巨细胞的互白素-8 (IL8) 通过CXCR2抑制T细胞免疫球蛋白和粘素域含蛋白3 (TIM3) 在结直肠癌 (CRC) 中的CD8+T细胞上,影响预后. 针对这个轴可以治疗先进的CRC.

关键词:
CD8 (((+) T细胞是T细胞中的一个.结肠直肠癌是一种癌症.IL8 IL8 IL8 IL8 IL8 IL8 IL8 IL8 IL8 IL8 IL8时间3 TIM3与瘤相关的巨细胞.

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