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来自奥地利阿尔卑斯山两大石泉流域的埃舍里希亚大肠杆菌分离物中抗菌素耐药性较低

Iris Schachner-Gröhs¹, Theresa Strohhammer¹, Christina Frick²

¹Institute of Hygiene and Applied Immunology - Water Microbiology, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Kinderspitalgasse 15, 1090 Vienna, Austria.

The Science of the total environment

|June 18, 2023

概括

在原始的奥地利泉源中,抗生素耐药性的细菌很少,反动物被确定为主要来源. 这凸显了管理良好的水资源在控制抗菌素耐药性传播方面的有效性.

科学领域:

环境微生物学环境微生物学
公共卫生公共卫生
评估水质水质的评估.

背景情况:

抗生素耐药性是一个日益增长的全球健康威胁.
水生生态系统有助于耐药细菌的传播.
纯净的水资源对公共卫生至关重要,但对耐药性的研究不足.

研究的目的:

评估来自受保护的奥地利石灰岩泉中的大肠杆菌 (E. coli) 的抗生素耐药性.
确定这些基本的地下水资源中抗生素耐药细菌的来源.
评估水域保护和管理对抗性水平的有效性.

主要方法:

季节性采样大肠杆菌来自13个地点,遍及两个石泉流域.
对551个大肠杆菌分离物进行抗生素耐药性查.
便污染评估和微生物源追踪.
与现有研究对石灰岩和山脉泉源的比较.

主要成果:

大肠杆菌只在夏季检测到.
抗生素耐药性的低患病率:3.4%对1-2类耐药,0.5%对3类耐药.
没有检测到对关键或最后一线抗生素的耐药性.
食动物被确定为耐药细菌的主要宿主.
保护的水域表现出比不那么原始的水域显著较低的阻力.

结论:

得到良好保护和管理的石泉表现出低水平的抗生素耐药性.
动物牲畜是这些地区耐药细菌的重要来源.
这种监测方法提供了对流域健康的整体观点,并与欧盟水质指令保持一致.

关键词:

抗生素耐药性抗生素耐药性美国大肠杆菌 (E. coli).便指标细菌便指标细菌便污染污染便污染破裂的水源层可能会导致水层破裂.微生物源追踪微生物源追踪多重电阻具有多重电阻

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