相关实验视频

Updated: Jul 26, 2025

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Left Anterior Descending Coronary Artery Ligation for Ischemia-Reperfusion Research: Model Improvement via Technical Modifications and Quality Control

Published on: December 16, 2022

总缺血时间和年龄作为STEMI中PCI失败的预测因素:系统性审查

Samantha R Kennedy¹, Yunki Kim¹, Scott Martin²

¹Sacred Heart University, Fairfield, CT, USA.

The American journal of the medical sciences

|June 18, 2023

概括

老年患者和较长的缺血时间增加了初级皮肤冠状动脉干预 (PCI) 后冠状动脉不回流的风险. 这种现象阻碍心脏组织的再输,需要新的指导方针和研究,以改善ST升高心肌梗塞 (STEMI) 患者的治疗结果.

科学领域:

心脏病学心脏病学
干预心脏病学干预心脏病学
心肌梗塞研究研究

背景情况:

初级穿皮冠状动脉干预 (PCI) 是对ST升高心肌梗塞 (STEMI) 的标准治疗方法.
在一次性PCI之后,心脏组织的再输血并不总是实现的,导致"无回流"现象.
影响no-reflow的因素,如缺血时间和患者年龄,需要进行系统的调查.

研究的目的:

系统地评估冠状动脉无逆流的总缺血时间和患者年龄的预测值.
评估晚年和长期缺血与没有回流后初级PCI之间的关联.

主要方法:

在多个数据库 (EBSCOhost,Cochrane) 进行系统的文献搜索.
由两名独立审查员使用Covidence.org.org进行选,选择和数据提取.
使用纽卡斯尔-太华尺度对8项选定的队列研究进行质量评估.

主要成果:

该审查包括8项研究,涉及7060名参与者.
60岁以上的患者患不复流的几率是1.53-2.53倍.
增加的整体缺血时间与1.147-4.655倍高的无反流发病率相关.

结论:

60岁以上的患有超过4-6小时的缺血时间的患者面临PCI失败的风险增加,因为没有反流.
在初级PCI后改善冠状动脉再输需要新的指导方针和进一步的研究来预防和治疗无反流.
识别高风险患者可以指导干预措施,以减轻无再流并发症.

关键词:

没有回流,总缺血时间.皮肤穿透冠状动脉干预 (PCI)

更多相关视频

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke

Published on: January 18, 2018

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Predicting Amputation using Local Circulating Mononuclear Progenitor Cells in Angioplasty-treated Patients with Critical Limb Ischemia

Published on: September 22, 2020

相关概念视频

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome I: Introduction

Acute Coronary Syndrome (ACS) encompasses a spectrum of heart conditions caused by sudden obstruction of coronary arteries, typically resulting from the rupture of an atherosclerotic plaque and subsequent thrombus (blood clot) formation. This obstruction can lead to partial or complete blockage of blood flow, causing varying degrees of myocardial ischemia or infarction.ACS includes the following clinical entities:Unstable Angina (UA)Non-ST-Elevation Myocardial Infarction (NSTEMI)ST-Elevation...

Ischemic Heart Disease: Overview

Ischemic Heart Disease: Overview

Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...