卵细胞采集和冷胚胎转移之间的时间间隔不会影响生殖结果
Ying Huang1, Jiangman Gao1, Yuanyuan Wang1
1Center for Reproductive Medicine, Department of Obstetrics and Gynecology, Peking University Third Hospital, Beijing, China; National Clinical Research Center for Obstetrics and Gynecology (Peking University Third Hospital), Beijing, China; Key Laboratory of Assisted Reproduction (Peking University), Ministry of Education, Beijing, China; Beijing Key Laboratory of Reproductive Endocrinology and Assisted Reproductive Technology, Beijing, China.
Reproductive biomedicine online
|June 18, 2023
概括
卵细胞采集和冷胚胎移植 (FET) 之间的时间不会影响活产率. 然而,避免在FET中不必要的延迟,以更快地实现怀孕.
科学领域:
- 生殖医学 生殖医学
- 在体外受精过程中受精.
背景情况:
- 在冷全部策略中,在卵细胞采集后,冷胚胎转移 (FET) 的最佳时间尚未确定.
- 了解卵细胞检索和FET之间的间隔的影响对于改善试管婴儿结果至关重要.
研究的目的:
- 调查卵细胞检索和冷胚胎移植 (FET) 之间的时间间隔是否会影响经过冷所有试管婴儿策略的患者的怀孕和新生儿结果.
主要方法:
- 一项回顾性研究分析了5995名患者,在结周期后接受了他们的第一个FET.
- 根据间隔,患者被分为立即 (≤40天),延迟 (>40至≤180天) 和逾期 (>180天) 组.
- 多变量回归分析评估了FET时间对活产率 (LBR) 的影响.
主要成果:
- 虽然逾期组最初的LBR比延期组低,但经过调整以考虑混因素后,这种差异在统计学上并不显著.
- 直接FET组在原始和调整后的分析中表现出与其他组可比的LBR.
- 在整个队列或特定子组中,没有发现FET时间对LBR有重大影响.
结论:
- 卵细胞采集和冷胚胎移植 (FET) 之间的时间间隔似乎不会影响生殖结果.
- 虽然延迟不会对结果产生负面影响,但避免不必要的延迟可以加快实现活产的时间.
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