药物使用与长期护理居民中跌倒和死亡率的关联:一个纵向队列研究
Hanna-Maria Roitto1,2,3, Ulla L Aalto4, Hanna Öhman4
1Department of Geriatrics, Helsinki University Hospital and University of Helsinki, Helsinki, Finland. hanna-maria.roitto@hel.fi.
BMC geriatrics
|June 18, 2023
概括
药物使用,特别是多药,增加了长期护理居民的跌倒风险. 过度的多药与较高的死亡率有关,这突显了需要谨慎处方的需要.
科学领域:
- 老年学是一门学科.
- 药理学 药理学是指药理学的学科.
- 公共卫生 公共卫生
背景情况:
- 在长期护理机构中,跌倒是一个很重要的问题.
- 了解药物使用和跌倒之间的关系对于居民安全至关重要.
研究的目的:
- 调查药物使用与跌倒发生率之间的关联.
- 探索药物使用,跌倒后果和长期护理居民死亡率之间的联系.
主要方法:
- 进行了一项纵向队列研究,涉及532名65岁以上的居民.
- 收集了药物数据,包括多药性 (5-10药) 和过度多药性 (>10药) 的数据.
- 跌倒,受伤,骨折,住院和死亡率分别在12个月和3年内跟踪,并进行了调整的分析.
主要成果:
- 总共记录了606次跌倒,随着使用药物的数量而增加的跌倒率.
- 多药和过度多药小组与非多药小组相比,出现明显更高的下降率.
- 阿片类药物和抗胆固醇药物与跌倒发生率的增加有关,而过度的多种药物预测了更高的全因死亡率.
结论:
- 多药,阿片类药物使用和抗胆固醇药物使用是长期护理下降的预测因素.
- 使用超过10种药物与增加全因死亡率有关.
- 长期护理的处方实践应该仔细考虑药物的数量和类型.
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