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转录因子E2F8通过NUSAP1调节DNA损伤,促进肝细胞癌中西斯普拉丁抗性

Jianqiao Kong1, Song Xu1, Peng Zhang1

  • 1Department of General Surgery, Xiangyang No.1 People's Hospital, Hubei University of Medicine, Xiangyang, China.

International journal of toxicology
|June 18, 2023
PubMed
概括

通过抑制DNA损伤修复,E2F8/NUSAP1通路促进肝细胞癌 (HCC) 中的西斯普拉丁耐药性. 针对这个轴可以提高化学疗法在HCC患者的有效性.

关键词:
造成的DNA损伤是DNA损伤.E2F8 E2F8 E2F8 E2F8 E2F8 E2F8 E2F8 E2F8我们的NUSAP1耐药性 抗性 抗性 抗性 抗性肝细胞癌是肝细胞癌.

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