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Updated: Jul 26, 2025

Cell-Specific Paired Interrogation of the Mouse Ovarian Epigenome and Transcriptome
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删除用于 de novo NAD生物合成的酶加速了卵巢衰老

Qingling Yang1,2,3, Hui Li1,2,3, Huan Wang1,2,3

  • 1Center for Reproductive Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Aging cell
|June 19, 2023
PubMed
概括

破坏 de novo 尼古丁胺胺氨基二核酸 (NAD+) 合成加速卵巢衰老,并损害小鼠的生育能力. 通过尼古丁胺 рибоoside (NR) 提高NAD+水平,改善了卵巢储备和卵细胞质量.

关键词:
在 de novo NAD+ 合成途径上.线粒体功能 线粒体功能卵巢衰老 卵巢衰老 卵巢衰老有活性氧物种的反应性氧物种.

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