脑血管和心血管对高温期间瓦萨尔瓦机动的反应
Blake G Perry1, Stephanie Korad1, Toby Mündel2,3
1School of Health Sciences, College of Health, Massey University, Wellington, New Zealand.
Clinical physiology and functional imaging
|June 19, 2023
概括
轻度高温症对瓦萨尔瓦操作 (VM) 的脑血管反应的影响最小. 在VM期间的大脑血液流动在很大程度上不受核心体温升高的影响,这表明大脑自调节得到保留.
科学领域:
- 生理学 生理学 生理学
- 心血管研究研究心血管研究
- 神经科学是一个神经科学.
背景情况:
- 瓦萨尔瓦操作 (VM) 导致血压发生显著变化.
- 这些变化在高温症期间更加明显.
- 在VM期间高温对大脑循环的影响尚不清楚.
研究的目的:
- 调查轻度高温症对VM期间大脑血管反应的影响.
- 为了确定在高温症中VM期间改变的平均动脉压 (MAP) 是否会影响大脑血流.
主要方法:
- 12名健康参与者在正常热量和轻度高热量期间接受了30mmHgVM的15秒.
- 使用摄入传感器监测核心温度.
- 中脑动脉速度 (MCAv) 和MAP连续记录.
- 计算了大脑自我调节指数.
主要成果:
- 超热症显著增加了核心体温.
- 在VM阶段I-III期间的MAP在高温症期间较低.
- 平均MCAv仅在高温的VMIIa阶段显著下降.
- 在这两种条件下,脉动率指数在VM后增加,在高温期间增加更大.
结论:
- 轻度高温并没有显著改变对VM的整体脑血管反应.
- 大脑血流调节在轻度高温症期间似乎在很大程度上保持不变,尽管在VM期间改变了MAP.
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