0.05%的氨酸控制了中国学童近视的进展:一个随机的3年临床试验
Qin Zhu1, Guang-Yong Tang2, Zhi-Juan Hua1
1Department of Pediatric Ophthalmology, Affiliated Hospital of Yunnan University, Kunming 650021, Yunnan Province, China.
International journal of ophthalmology
|June 19, 2023
概括
低剂量阿特罗平眼滴有效减缓近视的进展在儿童超过两年. 在停止治疗后,轴长度稳定,显示了持续的近视控制益处,没有显著的副作用.
科学领域:
- 眼科医生 眼科 眼科
- 儿科眼科医生 儿科眼科医生
- 临床研究 临床研究
背景情况:
- 近视是儿童日益严重的公共卫生问题.
- 有效的近视控制策略对于预防视力障碍至关重要.
- 低剂量氨酸在减缓近视的进展方面表现有前途.
研究的目的:
- 评价0.05%的阿特罗宾在控制中国儿童近视进展的有效性,超过两年.
- 为了评估阿特罗宾在治疗停止后对折射误差和轴长度的持续影响.
主要方法:
- 一项随机对照试验,涉及142名近视儿童.
- 治疗阶段为两年,每天服用0.05%的氨酸或安慰剂.
- 一年后续阶段没有治疗,以评估反弹效应.
主要成果:
- 在为期两年的治疗阶段,0.05%的氨酸显著降低了球体等效折射 (SER) 和轴长度 (AL) 的进展.
- 在停止使用阿托后,AL变化在两组之间没有显著差异.
- 与安慰剂相比,在治疗后的一年内,阿特罗平组的SER进展明显较低.
结论:
- 用0.05%的氨酸治疗两年,有效控制了儿童近视的进展.
- 控制近视的效果似乎在治疗停止后至少持续一年.
- 0.05%的氨酸是儿童近视控制的安全和有效的治疗选择.
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