在COVID-19患者中,新的和个性化的呼吸系统策略
Lucas Rodrigues de Moraes1, Chiara Robba2, Denise Battaglini2
1Laboratory of Pulmonary Investigation, Institute of Biophysics Carlos Chagas Filho, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.
Frontiers in medicine
|June 19, 2023
概括
本综述探讨了COVID-19患者的机械通风 (MV) 策略,包括非侵入性呼吸支持 (NRS) 和体外膜氧化 (ECMO). 它强调了了解COVID-19病理生理学的进展,并优化呼吸系统方法以获得更好的患者结果.
科学领域:
- 关键护理医学 关键护理医学
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
背景情况:
- 由SARS-CoV-2引起的COVID-19经常导致严重的呼吸衰竭,需要机械通风 (MV).
- 患有缺氧和呼吸障碍的患者,需要升级呼吸支策略.
- 了解COVID-19病理生理学和呼吸系统后果对于有效管理至关重要.
研究的目的:
- 审查COVID-19的非侵入性呼吸系统支持 (NRS) 设备和策略的证据.
- 通过COVID-19病理生理学来讨论个性化的机械通风 (MV) 管理.
- 将体外膜氧化 (ECMO) 作为救援疗法的使用置于背景.
主要方法:
- 对COVID-19中呼吸系统支持的当前证据的文献综述.
- 对病理生理学驱动的呼吸系统策略的分析.
- 评估体外膜氧化 (ECMO) 应用和个性化.
主要成果:
- 新的NRS工具提供了需要进一步研究的好处和缺点.
- 基于COVID-19病理生理学的个性化MV策略正在发展.
- 对于耐火性低氧血症来说,ECMO是一种有价值的救援选择,在其应用方面越来越多的专业知识.
结论:
- 优化NRS和MV对于管理COVID-19呼吸衰竭至关重要.
- 个性化,病理生理学知情通风改善了结果.
- 在严重病例中,ECMO起着至关重要的作用,需要量身定制的管理策略.
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