具有各种心脏代谢特征的年轻成年人心脏结构和功能
Swapnil D Parve1,2, Albina V Sineglazova1
1Primary Care and General Practice, Kazan State Medical University, Kazan, RUS.
年轻人的心脏代谢风险与心脏变化有关. 评估内脏脂肪,特别是在高危人群中,对于预防心血管疾病和识别心力衰竭表型至关重要.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 生物医学工程 生物医学工程
背景情况:
- 心血管疾病 (CVD) 是全球主要的死亡原因之一.
- 心脏代谢异常会影响心肌结构和功能.
- 关于年轻成年人具有不同风险概况的这些变化的数据有限.
研究的目的:
- 研究年轻成年人心脏代谢风险和心声回声学变化之间的关系.
- 使用心脏代谢疾病分期 (CMDS) 系统进行风险分层.
- 分析心脏代谢风险因素的性别差异.
主要方法:
- 包括191名被分为五个CMDS组的患者.
- 通过患者病史,体检和生物化学分析收集数据.
- 声心成像用于评估心脏结构和功能.
主要成果:
- 血压升高和高甘油三血症在男性中更为普遍.
- 逐渐增加的末端透缩体积 (EDV) 和末端抽缩体积 (ESV) 随着CMDS从0到3的喷射分数的减少.
- EDV和ESV与内脏脂肪,腰围和BMI有很强的相关性.
结论:
- 生物阻抗分析用于内脏脂肪评估,建议与CMDS一起进行,特别是对于CMDS 3个体.
- 患有过多内脏脂肪的CMDS 3患者 (新子组:CMDS 3过高) 面临心室扩大风险更高.
- 这些发现有助于识别心力衰竭的新型表型,其中保留了喷射分数.
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