线

概括

内异质性驱动黑色素瘤的演变,并影响对免疫检查点阻塞疗法的反应. 研究克隆亚线揭示了瘤可塑性如何影响治疗结果和免疫逃避.

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Treatment Resistant Cancers02:56

Treatment Resistant Cancers

Cancer is the second leading cause of death in the United States. A cancer cell is genetically unstable and hence can mutate faster. They can also modify their microenvironment and escape immune surveillance. The difficulties in treating cancer are further compounded by the emergence of rapid resistance to anticancer drugs. The most common ways to attain resistance in cancer cells include alteration in drug transport and metabolism, modification of drug target, elevated DNA damage response, or...
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