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Updated: Jul 26, 2025

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RNA螺旋酶DDX3 调节RAD51定位和修复Ewing肉瘤中的DNA损伤

Matthew E Randolph1,2, Marwa Afifi3, Aparna Gorthi4

  • 1Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY.

bioRxiv : the preprint server for biology
|June 19, 2023
PubMed
概括

通过影响RAD51局部化,RNA螺旋酶DDX3X (DDX3) 独特地影响了Ewing肉瘤中的DNA损伤修复. 抑制DDX3可以提高EWS对放射治疗的敏感性.

关键词:
这是DDX3 DDX3尤文肉瘤 (Ewing Sarcoma) 是一种癌症.在RAD51中使用RAD51.在RK-33中使用.RNA:DNA杂交的混合物双链 DNA 损伤修复同类的重组组合.电离辐射辐射的电离辐射.亚细胞局部化的局部化

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