DREADD

Sascha A L Mueller1, Jonathan A Oler1, Patrick H Roseboom1

  • 1Department of Psychiatry and the HealthEmotions Research Institute, University of Wisconsin School of Medicine and Public Health, Madison, WI 53719, USA.

概括

独家激活设计者药物 (DREADDs) 的设计者受体在中增加了杏仁体活动,导致了类似焦虑的行为. 这种灵长类模型显示了研究病态焦虑的长期潜力.