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Updated: Jul 26, 2025

Optimization of Synthetic Proteins: Identification of Interpositional Dependencies Indicating Structurally and/or Functionally Linked Residues
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什么能增强蛋白与蛋白的相互作用:残余相关联网络的分析和应用

Ta I Hung1,2, Yun-Jung Hsieh3,4, Wei-Lin Lu3

  • 1Department of Chemistry, University of California, Riverside, United States.

Research square
|June 19, 2023
PubMed
概括

设计蛋白质结合剂是一项挑战. 这项研究揭示了与相关运动发生突变的残留物优化了蛋白质相互作用,为治疗应用创造了高效的结合剂.

关键词:
二面相对应网络二面相对应网络.纳米分子粘合剂的使用帕帕因类蛋白酶是一种类似帕帕因的蛋白酶.基于蛋白质的抑制剂 基于蛋白质的抑制剂无处不在的变种.

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