不同形式的运动对执行功能和住院T2DM患者大脑血液动力学机制的急性影响:一项实体内研究
Haolin Wang1, Wei Tang2, Yanan Zhao1
1School of Sports Science and Physical Education, Nanjing Normal University, Nanjing, China.
Frontiers in public health
|June 19, 2023
概括
综合并发运动 (ICE) 和抵抗运动 (RE) 在2型糖尿病患者中显著改善了执行功能. 对于整体执行功能增强而言,ICE是首选的,而有氧运动 (AE) 则有利于刷新功能.
科学领域:
- 运动生理学 运动生理学
- 神经科学是一个神经科学.
- 临床医学 临床医学
背景情况:
- 2型糖尿病 (T2DM) 与执行功能受损有关.
- 了解不同运动方式对T2DM患者EF和脑血液动力学的急性影响对于有针对性的干预至关重要.
研究的目的:
- 研究有氧运动 (AE),抵抗运动 (RE) 和综合并发运动 (ICE) 对住院T2DM患者执行功能的急性影响.
- 探索与这些运动诱导的认知变化相关的潜在大脑血动力学机制.
主要方法:
- 在30名住院T2DM患者 (45-70岁) 中采用了主体内设计.
- 参与者在不同的日子接受了AE,RE和ICE,使用Stroop,More-odd转移和2-back测试来评估EF.
- 使用功能近红外光谱学 (fNIRS) 收集了脑血液动力学数据.
主要成果:
- 与基线相比,ICE和RE都显著改善了执行功能指标 (p < 0.05).
- 与AE相比,ICE和RE在抑制和转换功能方面表现出更好的改善.
- 运动增加了EF相关区域的大脑激活;ICE显示了DLPFC,FPA和OFC中的同步激活,DLPFC和FPA中的RE,主要在DLPFC中的AE.
结论:
- 建议综合并发运动 (ICE) 用于增强T2DM患者的整体执行功能.
- 有氧运动 (AE) 更有利于改善刷新功能.
- 认知功能的改善与特定脑部区域的脑血流激活之间存在协同关系.
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