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对H5N8禽流感病毒亚型的全球综述

Saba Rafique¹, Farooq Rashid², Sajda Mushtaq¹

¹SB Diagnostic Laboratory, Sadiq Poultry Pvt. Ltd, Rawalpindi, Pakistan.

Frontiers in microbiology

|June 19, 2023

概括

高致病性禽流感 (HPAI) H5N8对全球的家禽和人类健康构成重大威胁. 持续的监测和疫苗接种对于缓解HPAI H5N8疫情和保护粮食安全至关重要.

科学领域:

兽医病毒学兽医病毒学
流行病学流行病学
食品安全食品安全

背景情况:

像禽流感病毒一样,Orthomyxoviruses是负感RNA病毒,具有不稳定的细分基因组.
高致病性禽流感 (HPAI) 亚型H5N8在野生鸟类中出现,对家禽和人类健康构成重大风险.
全球HPAI H5N8疫情在家禽业造成了严重的金融危机,并影响了多个大陆的粮食安全.

研究的目的:

审查HPAI H5N8亚型的全球影响和传播.
强调HPAI H5N8对家禽生产和公共健康构成的威胁.
建议控制和预防HPAI H5N8.8的战略.

主要方法:

从GISAID中获取的HPAI H5N8病毒序列的分析.
对欧洲,欧亚,中东,非洲和美洲的HPAI H5N8疫情流行病学数据的审查.
评估病毒的遗传谱系 (clade 2.3.4.4b,Gs/GD谱系). 病毒的遗传谱系的评估.

主要成果:

HPAI H5N8,属于2.3.4.4b类 (Gs/GD系),已经在全球传播,影响了许多国家.
大陆范围的疫情表明病毒的广泛传播和持续威胁.
该病毒在家禽部门造成了重大经济损失,并引起了公众健康的担忧.

结论:

HPAI H5N8仍然是全球禽业和人类人口的持续威胁.
必须对野生和商业鸟类进行持续的血清学和病毒学监测,以及严格的生物安全.
建议在商业家禽中采用同源的疫苗接种策略,以对抗新兴菌株并减轻未来的疫情爆发.

关键词:

亚型 H5N8 亚型 H5N8 亚型禽流感病毒是禽流感病毒的一种病毒.控制和预防控制和预防流行病学流行病学监督监督监督监督监督监督监督监督监督监督监督监督监督监督监督监督监督监督

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