基于CNN的自动细分和放射学在对比度增强超声波图像上具有可靠性,用于脏瘤
Yin Yang1, Fei Chen2, Hongmei Liang1
1Department of Ultrasound, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Frontiers in oncology
|June 19, 2023
概括
卷积神经网络 (CNN) 模型,特别是UNet++,在自动分割对比增强超声波 (CEUS) 图像的瘤中表现出高准确性. 这种自动化细分对于放射性分析是可行的和可靠的.
科学领域:
- 医疗成像医学成像
- 人工智能在医学中的应用
- 在瘤学瘤学.
背景情况:
- 在对比度增强超声波 (CEUS) 图像中精确细分瘤对于诊断和治疗计划至关重要.
- 手动细分是耗时的,并且受观察者之间的变化影响.
- 卷积神经网络 (CNN) 在自动化医疗图像细分方面表现有前途.
研究的目的:
- 评估基于CNN的模型的可行性和效率,用于对瘤CEUS图像进行自动细分.
- 评估自动分割图像在放射性分析中的应用.
- 为了比较七个不同的CNN架构对这个任务的性能.
主要方法:
- 使用了来自94例瘤病例的3355张CEUS图像的数据集,使用手动细分作为基本真相.
- 七个CNN模型 (DeepLabV3+,UNet,UNet++,UNet3+,SegNet,MultilResUNet,Attention UNet) 被训练并进行了测试.
- 使用Pyradiomics提取放射性特征,并使用mIOU,DSC,精度和回忆来评估性能.
- 放射学特征的可靠性和可重复性使用皮尔森和类内相关系数 (ICC) 进行了评估.
主要成果:
- 所有七种CNN模型都实现了高性能,mIOU从81.97%到93.04%,DSC从78.67%到92.70%.
- 在所有指标中,UNet++模型表现最好 (mIOU: 93.04%,DSC: 92.70%).
- 从自动分割图像中提取的放射性特征显示出出色的可靠性和可重现性 (平均皮尔森系数为0.81-0.95,ICCs为0.77-0.92).
结论:
- 基于CNN的模型,特别是UNet++,对瘤CEUS图像的自动细分是有效的.
- 从这些自动化细分得出的放射学特征是可行的,可靠的临床应用.
- 建议进一步进行多中心验证,以确认这些发现.
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