脑静脉鼻血栓症患者预后不佳的特征:一个多中心回顾性研究
Yunli Zhang1,2, Yayuan Liu1,3, Bin Qin1,4
1Department of Neurology, The First Affiliated Hospital of Guangxi Medical University, Nanning, People's Republic of China.
Neuropsychiatric disease and treatment
|June 19, 2023
概括
从脑静脉鼻血栓形成 (CVST) 恢复不良与不常见的头痛和精神状态的改变有关. 血液学疾病和多个脑叶损伤也表明CVST患者的预后更差.
科学领域:
- 神经学 神经学
- 血管医学 血管医学
- 放射学 放射学是一门学科.
背景情况:
- 大脑静脉鼻血栓 (CVST) 是一种罕见但严重的疾病.
- 在CVST中预测患者的结果对于有效管理至关重要.
研究的目的:
- 确定与CVST患者恢复不良相关的特征,预测因素和成像特征.
- 分析影响成人CVST病例临床结果的因素.
主要方法:
- 追溯分析了290名成年CVST患者的队列.
- 患者被分为良好的 (mRS ≤2) 和不良的 (mRS >2) 预后组,基于排放修改的兰金尺度 (mRS) 评分.
- 后勤回归确定了与临床结果相关的因素.
主要成果:
- 头痛是最常见的症状 (76.21%),而局部头部/部感染是常见的并发症 (26.21%).
- 预后不佳与不常见的头痛 (OR: 2.769),精神状态改变 (OR: 0.122),血液学障碍 (OR: 0.191) 和多叶脑损伤 (OR: 0.166) 相关.
- 血栓的位置/数量和预后之间没有发现显著的相关性,但多叶损伤表明结果不佳.
结论:
- 头痛可能是保护因素,而意识改变则意味着CVST的预后不佳.
- 血液病与不良结果有关.
- 内损伤涉及多个叶片是CVST中临床预后不佳的重要预测因素.
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