产前社会环境暴露和自闭症谱系障碍:一个混乱的网络
Aisha S Dickerson1, Asha S Dickerson2
1Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA.
Child development perspectives
|June 19, 2023
概括
环境因素,包括产前暴露和心理社会压力因素,可能会导致自闭症谱系障碍 (ASD) 风险. 需要进行研究来理解这些联系,并解决脆弱人群的环境正义问题.
科学领域:
- 神经发育障碍 神经发育障碍
- 环境健康 环境健康
- 遗传学 遗传学 是一个
背景情况:
- 自闭症谱系障碍 (ASD) 具有强烈的遗传成分,但环境影响也与之有关.
- 双胞胎研究表明,非遗传因素有助于ASD病因.
- 许多环境和心理社会暴露与非典型的神经发育有关.
研究的目的:
- 总结了产前环境暴露与ASD之间报告的关联.
- 审查与ASD相关的化学,空气污染,职业和心理社会压力因素.
- 识别研究缺口,并在ASD研究中倡导环境正义.
主要方法:
- 对环境暴露和ASD研究的文献综述.
- 关于产前因素与神经发育障碍之间报告的关联的综合.
- 分析环境正义对弱势群体的影响.
主要成果:
- 产前空气污染物,化学物质暴露和心理社会压力因素与ASD有关.
- 突出了不同研究报告的关联的一致性.
- 在边缘化社区和低收入国家,暴露和研究存在显著差异.
结论:
- 环境因素在ASD病因学中起作用,与遗传倾向相互作用.
- 进一步的研究对于阐明ASD的特定环境风险至关重要.
- 解决环境正义问题和减少暴露差异对于弱势群体至关重要.
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