妊娠期间限制和过度养会降低整个成熟期后代的生长
Nicole M Tillquist1, Sarah A Reed1, Mia Y Kawaida1
1Department of Animal Science, University of Connecticut, Storrs, CT 06269, USA.
Translational animal science
|June 19, 2023
概括
雌羊的母亲营养不良限制或过度养后代的成长到成熟. 虽然代谢变化很小,但母亲的饮食显著影响了后代的体重和骨发育.
科学领域:
- 动物科学动物科学
- 营养科学 营养科学
- 生殖生物学 生殖生物学
背景情况:
- 孕期母亲的营养对于后代的发育和长期健康至关重要.
- 了解母亲饮食失衡对后代生长和新陈代谢的影响,对于畜牧业生产和人类健康至关重要.
研究的目的:
- 研究母亲的营养状况 (受限制,控制或过度养) 对绵羊后代的成长,身体组成和代谢参数的长期影响.
- 为了确定母亲的饮食是否影响后代的食效率和葡萄糖代谢.
主要方法:
- 在怀孕期间,羊被养了60% (受限制),100% (控制) 或140% (过度养) 的NRC要求.
- 后代 (羊羔) 被监测到体重,血液参数,葡萄糖耐受性和剩余料摄入量 (RFI).
- 尸体分析包括身体形态学,器官重量,骨矿物质密度 (BMD) 和骨长度.
主要成果:
- 在整个研究期间,受限制和过度养的后代与对照人群相比,体重减少.
- 受到限制的后代显示肝脏重量可能增加,丸重量减少,骨质量和骨长度减少.
- 母亲的饮食没有显著影响后代的养效率,肌肉质量,脂肪沉积或关键血脂概况,尽管葡萄糖耐受性和瘦素水平显示出轻微的变化.
结论:
- 母亲的营养不良,无论是限制的还是过度的,都会对后代的生长和骨发育产生负面影响.
- 后代的代谢适应似乎很小,这表明其他补偿机制可能参与缓解或应对母亲的饮食挑战.
- 需要进一步的研究,以阐明母亲营养状况对后代健康的长期影响的确切机制.
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