相关实验视频
Updated: Jul 26, 2025

09:36
Assessment of Child Anthropometry in a Large Epidemiologic Study
Published on: February 2, 2017
27.2K
在老年人群中,通过体重指数或体脂指数评估的超重相关的大脑变化:PROOF研究
Radwan Kassir1, Pierre Gimet2,3, David Hupin2,3
1Department of Digestive Surgery, CHU Félix Guyon, Saint Denis, Saint-Étienne, France.
Frontiers in endocrinology
|June 19, 2023
概括
在老年人中,大脑结构的变化与肥胖有关,无论使用哪种测量方法. 小脑与老年人肥胖有显著的关联.
科学领域:
- 神经科学是一个神经科学.
- 老年学是一门学科.
- 肥胖问题研究研究
背景情况:
- 肥胖是一个复杂的健康问题,对大脑的作用不完全了解,特别是在老年人中.
- 衰老会改变身体成分 (脂肪与瘦肉),可能会改变与年轻人相比,大脑与肥胖的关系.
研究的目的:
- 研究大脑结构与老年人肥胖之间的关系.
- 用身体质量指数 (BMI) 和身体脂肪指数 (BFI) 来比较肥胖与大脑体积的关联.
主要方法:
- 使用3D磁共振成像 (MRI) 和双能X射线吸收计 (DXA) 在273名来自PROOF群体的老年人 (75岁以上) 中.
- 采用基于voxel的形态测量来分析与肥胖指标相关的局部大脑体积差异.
主要成果:
- 较高的BMI和BFI与左小脑灰质 (GM) 的增加相关.
- 小脑中的白质体积增加和右侧中枢轨道环附近与更高的BMI和BFI有关.
- 体重指数与大脑干转基因增加有关,而BFI与左侧中圈转基因增加有关;没有观察到白质量的减少.
结论:
- 在老年人中,大脑与肥胖的关系在不同肥胖指标 (BMI和BFI) 上是一致的.
- 小脑结构与老年人肥胖有显著的关联.
- 虽然一些顶区域显示了轻微的关联,小脑却成为与老年人肥胖相关的关键大脑区域.
相关概念视频
Obesity
549
The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
549
Aging
89
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
89
The Effect of Aging on Tissues
2.2K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
2.2K

