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在慢性感染E型肝炎患者的索福斯布维尔治疗期间出现与耐药性相关的变异

André Gömer1, Mara Klöhn1, Michelle Jagst1,2

  • 1Department of Molecular and Medical Virology, Ruhr University Bochum, Bochum, Germany.

Hepatology (Baltimore, Md.)
|June 19, 2023
PubMed
概括

索福斯布维尔治疗慢性乙型肝炎病毒 (HEV) 感染的免疫功能低下的患者,这些患者选择了耐药变体. 病毒种群的多样性推动了耐药性的出现,特别是A1343V替代,阻碍了持续的病毒学反应.

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