视觉幻觉现象的神经心理学相关性在莱维体病中的视觉幻觉现象
Isha Puntambekar1, Jennifer A Foley1,2
1Department of Neuropsychology, National Hospital for Neurology and Neurosurgery, London, UK.
International journal of geriatric psychiatry
|June 19, 2023
概括
在莱维体病 (LBD) 中的视觉幻觉与认知障碍有关. 复杂的视觉幻觉 (CVH) 涉及视觉空间和执行功能障碍,而轻微的视觉幻觉 (MVH) 显示视觉空间缺陷,表明后皮层参与.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 精神病学是一个精神病学.
背景情况:
- 视觉幻觉 (VH) 是莱维体病 (LBD) 的标志,影响预后.
- 认知障碍 (CI) 是已知的风险因素,与LBD中的VH相关.
- 在LBD中驱动VH的精确机制仍然不完全理解.
研究的目的:
- 为了调查认知障碍 (CI) 的特定模式与视觉幻觉 (VH) 频谱在莱维体疾病 (LBD) 相关.
- 为了探索不同的VH现象学亚型是否与明显的认知缺陷相关.
主要方法:
- 一个回顾性比较30名LBD患者轻微VH (MVH),13名复杂VH (CVH) 和32名没有VH的对照.
- 认知领域的评估,包括高阶视觉处理,记忆,语言和执行功能.
- 对VH群体的分层化,以检查现象学亚型及其认知相关物.
主要成果:
- 与对照组相比,患有CVH的LBD患者表现出视觉空间和执行功能受损.
- 带有MVH的LBD患者也表现出视觉空间领域的缺陷.
- 在患有特定幻觉现象的患者组之间,没有发现受影响的认知领域的显著差异.
结论:
- 在LBD中,复杂的VH与前皮下皮层和后皮层功能障碍有关.
- 轻微的VH可能先于或与后皮层功能障碍相关,特别影响视觉空间能力.
- 了解这些CI模式可以了解LBD中VH的潜在机制.
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