在患有1型肌肉性缩症和杜申肌肉缩症的患者中,开口咬伤缺陷和面部功能障碍
Christina Havner1,2, Anna Ödman Roussakis2, Lotta Sjögreen2,3
1Department of Orthodontics, Institute of Odontology, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Journal of neuromuscular diseases
|June 19, 2023
概括
开口咬伤 (OB) 常见于1型肌性缩症 (DM1) 和杜申肌性缩症 (DMD),与特定的口腔面部功能障碍有关. 这凸显了为量身定制的治疗策略提供多学科护理的需要.
科学领域:
- 神经学 神经学
- 牙科 牙科是指牙科的专业.
- 遗传学 是一个遗传学.
背景情况:
- 开口咬伤 (OB) 是一种经常发生的与口腔面部功能障碍相关的缺陷,特别是在神经肌肉疾病中.
- 了解特定肌肉发育不良症的OB患病率和口腔面部特征对于患者管理至关重要.
研究的目的:
- 在患有1型肌肉性缩症 (DM1) 和杜申肌肉缩症 (DMD) 的患者中调查开口咬伤 (OB) 的患病率.
- 开发和比较这些患者群体的口腔表情功能障碍概况.
主要方法:
- 一项数据库研究包括143名DM1患者和99名DMD患者.
- 使用Mun-H-Center问卷,观察图表和北欧耳鼻面部查测试 (NOT-S) 来评估耳鼻面部功能障碍.
- OB被分类 (侧向,前向,严重前向),并进行统计分析来比较患病率和关联.
主要成果:
- 在DM1 (37%) 和DMD (49%) 两组之间,OB患病率显著不同 (p=0.048).
- 侧面OB (LOB) 在DMD中比DM1 (<1%) 更为普遍 (18%) 并与巨和闭嘴姿势相关.
- 前部OB (AOB) 和严重的前部OB (AOBS) 分别与缺陷的嘴唇和肌有关.
结论:
- 开口咬伤缺陷在DM1和DMD患者中很普遍,与明显的口腔面部功能障碍相关.
- 这项研究强调了针对个性化治疗计划进行多学科评估的必要性,以提高 orofacial 功能.
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