在患有超小大动脉环形的患者中进行过导管大动脉植入
Gabriela Tirado-Conte1, Josep Rodés-Cabau2, Juan F Oteo3
1Cardiovascular Institute, Hospital Clínico San Carlos IdISSC, Madrid, Spain.
概括
通过导管的大动脉植入 (TAVI) 对患有小大动脉环 (SAA) 的患者是安全的. 自扩展 (SEV) 在这个患者群体中显示出比气球扩展 (BEV) 更好的结果.
科学领域:
- 心血管医学 心血管医学
- 干预心脏病学 干预心脏病学
- 医疗器械 医疗器械
背景情况:
- 小的大动脉环 (SAA) 增加了在大动脉置换后假体-患者不匹配 (PPM) 的风险.
- 有限的数据存在于超小的大动脉环 (extra-SAA) 患者的跨导管大动脉植入 (TAVI) 结果.
研究的目的:
- 评估TAVI在患者外SAA的安全性和有效性.
- 在这个群体中,比较自我膨胀 (SEV) 和气球膨胀 (BEV) 之间的结果.
主要方法:
- 一项多中心注册研究,对接受TAVI的SAA外患者进行了研究.
- 额外SAA定义为大动脉环面积<280mm2和/或周长<60mm.
- 使用门学术研究联盟-3标准在30天后评估的终点:设备成功和早期安全性.
主要成果:
- 包括150名患者;110人接受了SEV.
- 与SEV (96.4%) 相比,BEV (77.5%) 的技术成功率更高.
- 30天的设备成功率高于SEV (85.5%) 与BEV (70.0%);严重的PPM低于SEV (9.0%) 与BEV (24.0%).
结论:
- 对于SAA以外的患者来说,TAVI是一种安全和可行的选择.
- 与BEV相比,SEV表现出卓越的程序成功,30天的设备成功,并减少了严重的PPM.
- 严重的PPM对长期死亡率或心力衰竭再入院没有显著的影响.
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