维生素B12补充剂改善了中年和老年患者的认知功能,这些患者的认知功能受损
Li Zhou1, Xue Bai2, Jiagui Huang1
1Department of Neurology. The First Affiliated Hospital of Chongqing Medical University.
Nutricion hospitalaria
|June 19, 2023
概括
维生素B12补充剂显著改善了认知障碍患者的神经心理功能,特别是注意力和计算能力. 这表明维生素B12可能会增强那些经历认知衰退的人的额叶功能.
科学领域:
- 神经学 神经学
- 营养神经科学 营养神经科学
背景情况:
- 认知障碍影响了中年和老年人口的很大一部分.
- 神经心理缺陷是认知能力下降的一个标志.
- 越来越多的人认为,维生素B12缺乏是导致认知障碍的潜在因素.
研究的目的:
- 研究维生素B12补充剂在改善神经心理功能方面的疗效.
- 评估维生素B12对认知障碍患者疾病进展的影响.
- 为了确定维生素B12补充是否可以增强额叶功能.
主要方法:
- 一项前性病例控制研究,涉及115名认知障碍参与者.
- 随机分配到维生素B12治疗组 (n=58) 和对照组 (n=57).
- 在基线和六个月后使用MMSE和MoCA进行神经心理评估.
主要成果:
- 维生素B12治疗组在注意力和计算方面显著改善 (p < 0.01).
- 在治疗组中观察到增强的视觉结构能力 (p < 0.05).
- 与对照组相比,神经心理功能总体有所改善.
结论:
- 维生素B12补充剂在改善前额叶功能方面显示出有前途的前额叶功能在认知能力下降的个体.
- 对所有被诊断患有认知障碍的患者来说,调查维生素B12水平至关重要.
- 这项研究支持维生素B12在维持认知健康方面的作用.
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