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腹部扩散权重MRI与同时多切片获取:明显扩散系数测量的协议和可重复性

Zheng Ye¹, Shan Yao¹, Ting Yang¹

¹Department of Radiology, West China Hospital, Sichuan University, Chengdu, China.

Journal of magnetic resonance imaging : JMRI

|June 19, 2023

概括

同时多切片扩散权重成像 (SMS-DWI) 的规范化表面扩散系数 (ADC) 值显示在不同MRI供应商和呼吸技术之间具有良好的一致性和可重复性. 这表明正常化的ADC可以作为评估腹部变化的可靠生物标志物.

科学领域:

放射学放射学是一门学科.
医疗成像医学成像
扩散加权成像是一种扩散加权成像技术.

背景情况:

同时多切片扩散加权成像 (SMS-DWI) 为腹部MRI提供了更短的获取时间.
定量成像生物标志物的标准化对于可靠的临床解释至关重要.

研究的目的:

评估从腹部SMS-DWI的明显扩散系数 (ADC) 测量结果的一致性和可重复性.
为了比较使用不同MRI供应商和呼吸技术 (喘息与自由呼吸) 获得的ADC值.

主要方法:

这项前性研究涉及20名志愿者和10名患者.
采购腹部SMS-DWI在3.0T使用两个供应商和呼吸屏蔽和自由呼吸方案.
在肝脏,胰腺,脏和脏中测量非正常化和脏正常化的ADC值.

主要成果:

非正常化的ADC值在肝脏和胰腺中显示出显著的差异,但在脏或脏中没有显著差异.
在所有测量器官中,标准化的ADC值在供应商和呼吸方案之间没有显著差异.
观察到良好的到优秀的互读器一致性 (ICC 0.861-0.983) 和可重复性 (CV 3.55%-13.98%).

结论:

从腹部SMS-DWI中规范化的ADC值在不同供应商和呼吸方案之间似乎是可比的.
规范化的ADC测量显示出良好的一致性和可重现性,支持它们作为定量生物标志物的使用.
超过大约8%的ADC变化可以被认为是疾病或治疗评估的可靠指标.

关键词:

在腹部,腹部,腹部.看似的扩散系数.扩散权重成像技术的使用.可复制性的可复制性同时的多片切片.

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