Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Antidotes01:17

Antidotes

700
Antidotes are medicinal substances used to counteract the harmful effects of toxins or drugs in the body. They function in various ways, each uniquely designed to combat specific toxic compounds.
Specific antidotes operate by inhibiting the enzymes that control biochemical pathways, reducing the production of harmful metabolites.
An example of an antidote is atropine, which counteracts the detrimental effects of cholinesterase inhibitors. It achieves this by deactivating muscarinic receptors,...
700

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Immunologically Effective Chiral Polymers to Potentiate Anti-Cancer Immune Responses.

Polymer science & technology (Washington, D.C.)·2026
Same author

Synthetic Polymers for Drug, Gene, and Vaccine Delivery.

Polymer science & technology (Washington, D.C.)·2026
Same author

Prospects of Four-Dimensional Printing of Polymers for Biomedical Engineering.

Polymer science & technology (Washington, D.C.)·2026
Same author

Antioxidant Proline Carbon Dot-Composited Poly(L-methionine) Hydrogel Restores Mitophagy to Alleviate Cellular Senescence in Intervertebral Disc Degeneration.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

A Structurally Stabilized Lipopolymer Nanoplatform Targeting Pan-Tissue Antigen-Presenting Cells Enables Durable in situ mRNA Cancer Immunotherapy.

Advanced materials (Deerfield Beach, Fla.)·2026
Same author

Thermo-sensitive poly(L-methionine) hydrogel facilitates regenerative repair of diabetic wounds by modulating immune microenvironments.

Biomaterials science·2026

相关实验视频

Updated: Jul 26, 2025

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
14:20

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Published on: June 13, 2014

16.8K

聚合物纳米抗剂 聚合物纳米抗剂

Jiazhen Yang1,2, Hongjie Li1,2, Haoyang Zou1

  • 1Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, 5625 Renmin Street, Changchun, 130022, P. R. China.

Chemistry (Weinheim an der Bergstrasse, Germany)
|June 19, 2023
PubMed
概括
此摘要是机器生成的。

聚合物纳米抗剂为中毒提供了一个有希望的现场排毒策略,通过物理或化学相互作用中和毒素. 由于模型开发和药理动力学不确定性,临床转化仍然存在挑战.

关键词:
生物仿真许可证的许可证.化学结合 化学结合 化学结合临床实践中的临床实践身体互动 身体互动聚合物纳米抗剂的方法

更多相关视频

Formulation of Diblock Polymeric Nanoparticles through Nanoprecipitation Technique
06:47

Formulation of Diblock Polymeric Nanoparticles through Nanoprecipitation Technique

Published on: September 20, 2011

37.4K
Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization
06:26

Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization

Published on: January 24, 2025

1.1K

相关实验视频

Last Updated: Jul 26, 2025

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
14:20

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Published on: June 13, 2014

16.8K
Formulation of Diblock Polymeric Nanoparticles through Nanoprecipitation Technique
06:47

Formulation of Diblock Polymeric Nanoparticles through Nanoprecipitation Technique

Published on: September 20, 2011

37.4K
Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization
06:26

Synthesis of Stimuli-responsive Nanogels using Aqueous One-step Crosslinking and Co-nanopolymerization

Published on: January 24, 2025

1.1K

科学领域:

  • 纳米技术纳米技术
  • 毒理学 毒理学 毒理学
  • 聚合物科学 聚合物科学

背景情况:

  • 酒精中毒是导致意外死亡的全球主要原因.
  • 目前的治疗方法通常依赖于非特异性的体外方法来清除毒素.
  • 具体的抗药物是有限的,强调了需要新的治疗策略.

研究的目的:

  • 审查聚合物纳米抗剂的排毒机制.
  • 探索纳米抗剂临床应用的机遇和挑战.
  • 讨论纳米干预策略在管理中毒方面的潜力.

主要方法:

  • 关于纳米抗剂策略的现有文献的审查.
  • 在现场排毒机制的分析 (物理相互作用,化学结合,生物模拟清除).
  • 讨论临床翻译方面的挑战,包括模型开发和药理动力学.

主要成果:

  • 聚合物纳米抗剂显示出在现场中和异生菌的潜力.
  • 纳米干预策略提供了其他排毒途径.
  • 在将纳米抗剂从概念验证转化为临床实践方面存在重大障碍.

结论:

  • 聚合物纳米抗剂在毒理学和急诊医学领域是一个有前途的前沿.
  • 需要进一步的研究来克服临床相关性和药理动力学理解方面的挑战.
  • 纳米干预策略有可能彻底改变中毒管理.