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预测中心节律失常的预测因素在患有中心脱落的患者中:一个元分析
George Bazoukis1,2, Athanasios Saplaouras3, Konstantinos Vlachos3
1From the Department of Cardiology, Larnaca General Hospital, Larnaca, Cyprus.
Cardiology in review
|June 19, 2023
概括
风险较高的心律失常患者可以使用特定的标记物来识别. 较低的T波逆转,QTc间隔和晚期加多增强是风险分层的关键指标.
科学领域:
- 心脏病学 心脏病学
- 心脏电生理学 心脏电生理学
- 医疗成像医学成像
背景情况:
- 关脱落 (MVP) 影响2-3%的人口.
- MVP患者面临心室节律失常的风险较高.
- 准确的风险分层对于管理MVP患者至关重要.
研究的目的:
- 确定MVP患者心律失常风险分层的容易获得的标志物.
- 进行对MVP和心室节律失常现有研究的元分析.
- 为临床实践提供基于证据的建议.
主要方法:
- 根据PRISMA指南进行的元分析.
- 包括23项相关研究.
- 对各种临床和成像标志物的数据进行定量合成.
主要成果:
- 晚期的加多增强 (LGE),更长的QTc间隔,较低的T波反转,心肌环状断层 (MAD),左下心室喷射分数 (LVEF),胆叶MVP和增加的心室叶片厚度与心室节律失常有关.
- 性别,QRS持续时间和 mitra 传单的长度并不是显著的风险因素.
- 与RR或平均差异和p值发现了显著的关联.
结论:
- 较低的T波逆转,QTc间隔,LGE,LVEF,MAD,胆叶片MVP和心肌叶片厚度对于MVP失常风险分层有价值.
- 这些标记物在临床环境中很容易获得.
- 建议进行进一步的前性研究,以改进风险分层.
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