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经过分阶段与协调性乳房手术和双边卵管切除术后的术后结果

Sudheer R Vemuru¹, Michael Bronsert², Kristen Vossler³

¹Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.

Annals of surgical oncology

|June 19, 2023

概括

协调乳腺外科手术与双边沙卵巢切除术 (BSO) 增加了乳腺切除术患者的并发症,但并没有增加乳腺切除术患者的并发症. 在协调和分阶段程序之间,医疗保健成本仍然相似.

科学领域:

在瘤学瘤学.
手术瘤学手术瘤学
妇科瘤学妇科瘤学

背景情况:

比较协调与分阶段的乳房手术和双边salpingo-oophorectomy (BSO) 的结果.
评估术后并发症率和医疗费用.
评估高风险个体的患者管理策略.

研究的目的:

为了与BSO进行协调和分阶段的乳房手术之间的术后并发症率进行比较.
为了比较协调和分阶段程序的2年总体医疗费用.
确定受益于协调外科手术方法的患者子组.

主要方法:

使用了MarketScan行政数据库 (2010-2015年).
包括患有乳腺癌或BRCA突变的成年女性患者,接受BSO和乳腺手术.
基于同时 (协调) 与单独 (分阶段) 的BSO和乳房手术的结果进行了比较.

主要成果:

协调手术组 (9.7%) 的术后并发症比分阶段组 (90.3%) (24.0%对17.7%,p < 0.01) 的高.
在协调组中,风险调整后的并发症几率更高 (OR1.37,p = 0.02).
在风险调整之前和之后,医疗保健总费用在各组之间是相似的.

结论:

与BSO协调乳房手术增加了乳房切除患者的并发症,但不是乳房切除患者.
无论手术时间如何,医疗费用都是可比的.
研究结果支持高风险患者就手术时间的共同决策.

关键词:

有协调的手术.进行乳腺切除术.降低风险的手术可以减少风险.在Salpingo-oophorectomy中进行卵管切除术.

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