关于放射学的元分析概述:需要更多的证据来支持临床翻译
Jingyu Zhong1, Junjie Lu2, Guangcheng Zhang3
1Department of Imaging, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200336, China.
Insights into imaging
|June 19, 2023
概括
这项研究审查了放射学研究的元分析,发现质量不够优,临床使用的令人信服的证据有限. 需要更多的研究来将放射学转化为实际的临床工具.
科学领域:
- 无线电学 (Radiomics) 是一种辐射学.
- 医学成像分析 医学成像分析
- 系统审查是系统的审查.
背景情况:
- 放射学从医学图像中提取定量特征.
- 它的临床实用性正在调查中,需要对现有研究进行质量评估.
研究的目的:
- 提供关于放射学研究的元分析的概述.
- 评估放射学研究的质量和证据水平.
主要方法:
- 系统地搜索同行评审的数据库和预版服务器.
- 包括系统审查与放射学研究的元分析.
- 使用PRISMA,AMSTAR-2和ROBIS工具评估报告,方法以及偏见风险.
- 对临床应用的证据水平的评级.
主要成果:
- 确定了44个带有元分析的系统审查.
- 报告遵守率 (PRISMA) 的平均值为65%.
- AMSTAR-2表示低 (5) 或临界低 (39) 置信度.
- 在28个评论中,ROBIS显示存在偏见的高风险.
- 只有3个元分析 (共53个) 证明了临床使用的令人信服的证据,包括在质瘤和肺炎分化中的特定应用.
结论:
- 放射学系统性审查显示的质量不足于最佳.
- 有限数量的放射学应用有令人信服的证据证明其临床用途.
- 目前的证据不足以实现广泛的临床采用,需要进一步将学术研究转化为临床实践.
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