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通过14-3-3对PEAK3伪激酶支架的调节进行结构性洞察

Hayarpi Torosyan1,2, Michael D Paul1, Antoine Forget3,4

  • 1Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA, 94158, USA.

Nature communications
|June 19, 2023
PubMed
概括

PEAK3伪基因酶二元化结合14-3-3蛋白质,形成一个独特的接口,调节细胞行为和癌症进展. 这种结构洞察力澄清了PEAK3脚手架及其相互作用.

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