激光与Anti-VEGF对比:治疗预产性视网膜病变的范式转变
M Elizabeth Hartnett1, Andreas Stahl2
1Byers Eye Institute at Stanford University, Stanford University, 2452 Watson Court, Palo Alto, CA, 94303, USA. me.hartnett@stanford.edu.
Ophthalmology and therapy
|June 19, 2023
概括
过早性视网膜病变 (ROP) 是由于血管生长异常导致儿童失明的原因. 目前的治疗重点是激光治疗和抗VEGF注射来控制这种情况.
科学领域:
- 眼科医生 眼科 眼科
- 新生儿科学 新生儿科学
- 血管生物学 血管生物学
背景情况:
- 早产视网膜病变 (ROP) 是儿童失明的主要原因.
- 从历史上看,ROP与视网膜新血管化和脱落有关.
- 现代理解包括ROP早期的血管生长不足,特别是早产婴儿存活.
研究的目的:
- 审查对早产儿视网膜病变的不断发展的理解和当前的管理.
- 突出ROP的既定和新兴治疗策略.
主要方法:
- 关于ROP病原和治疗演变的文献综述.
- 对ROP的历史和当前治疗方式的分析.
主要成果:
- ROP的理解已经扩大到超越新血管化,包括早期的血管不发育.
- 目前有两种主要治疗方法:激光光凝 (自20世纪90年代以来的标准) 和抗VEGF注射 (2007年以来).
结论:
- 在ROP中控制血管扩散对于治疗必要的眼睛仍然至关重要.
- 激光治疗和抗VEGF注射是目前ROP管理的主要支柱.
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