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动脉中的生物力学特征:使用微气泡的亚声波排放进行非侵入性评估

Rui Li¹, Yukang Zhang¹, Shuai Zheng¹

¹Department of Ultrasound, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Medical physics

|June 20, 2023

概括

低辅助压力估计 (SHAPE) 技术揭示了正常动脉中的压力分布不均,特别是动脉分叉处的振幅更高. 这种非侵入性方法可能为血管生物力学提供新的见解.

科学领域:

生物医学工程生物医学工程
心血管成像 - 心血管成像
医学超声波医学超声波

背景情况:

脑卒中与大脑动脉样硬化斑有关,由于生物力学因素,这些斑块通常在动脉分叉处形成.
阴道鼻的定量血液动力应激分析对于理解斑块的发展至关重要.
超声波对比剂产生对压力变化敏感的亚声波,与环境压力相反.

研究的目的:

利用亚声辅助压力估计 (SHAPE) 技术来评估动脉的水力动力学特征.
通过使用SHAPE.来研究动脉光内的压力变化.

主要方法:

对13名参与者的26条正常动脉进行前性研究 (2021年5月至12月).
进行了双边动脉例行超声波和SHAPE检查.
对远端常见动脉,动脉分叉和动脉球的纵向和横向扫描进行了分析,以检测低调幅度.

主要成果:

在动脉中观察到亚波幅的不均分布.
在动脉分叉 (CAB) 检测到更高的亚波幅.
在CAB顶部平面 (9.72±4.31dB) 上最大的亚和弦梯度;在外侧层 (-56.40±6.31dB) 中,较高的平均亚和弦振幅.

结论:

SHAPE技术有效地反映了血管组织内的压力变化.
SHAPE提供了一种潜在的非侵入性监测方法,用于评估血管机械特征.
这项技术可能为评估与血液动力学压力相关的条件提供新的途径.

关键词:

一个形状的形状.美国美国美国生物力学生物力学動脈動脈 - 頸動脈動脈压力就是压力,压力就是压力.

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