语言工作记忆-平衡程序训练改变了左状回旋休息状态的功能连接:一个随机的临床试验研究对儿童的阅读障碍
Mehdi Ramezani1,2, Saeed Behzadipour3,4, Angela J Fawcett5
1Nursing and Midwifery Care Research Center, Iran University of Medical Sciences, Tehran, Iran.
Dyslexia (Chichester, England)
|June 20, 2023
概括
这项研究表明,口头工作记忆平衡 (VWM-B) 训练增强了阅读障碍儿童左状回膜的功能连接. 这种改善与更好的阅读,记忆和平衡能力有关.
科学领域:
- 神经科学是一个神经科学.
- 认知科学 认知科学
- 发展心理学 发展心理学
背景情况:
- 左状回旋对于阅读获取至关重要,影响阅读,命名,工作记忆 (WM) 和平衡.
- 阅读障碍经常与这些领域的挑战有关,这表明潜在的神经支.
- 以前的研究表明,有针对性的干预措施可以积极影响阅读和认知功能.
研究的目的:
- 研究一种新的口头工作记忆平衡 (VWM-B) 培训计划对患有阅读障碍的儿童左状环的功能连接性的影响.
- 评估VWM-B培训是否导致阅读能力,工作记忆能力和姿势控制的可衡量的改善.
主要方法:
- 功能磁共振成像 (fMRI) 和行为评估在15次培训课程之前和之后进行.
- 阅读障碍儿童被分为一个实验组 (接受VWM-B培训) 和一个对照组.
- 进行了统计分析,以比较组之间的功能连接和行为措施的变化.
主要成果:
- VWM-B训练显著增加了左侧状回环与左侧前状状皮质,小脑 (Crus II) 和左侧中额头回环的功能连接.
- 与对照组相比,实验组在阅读和命名能力,工作记忆能力和姿势控制方面表现出显著的改善.
- 这些神经和行为变化表明,VWM-B干预对参与阅读和认知功能的关键大脑区域产生了直接影响.
结论:
- 这些发现凸显了左状绕在阅读能力及其在针对性干预后的可塑性方面的关键作用.
- 这项研究提供了大脑小脑参与阅读障碍的证据,并支持VWM-B培训计划在改善阅读障碍儿童多种认知和运动功能的有效性.
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