在COVID-19幸存者中,呼吸不良的运动反应和心理健康症状
Kathryn M Milne1,2, Juthaporn Cowan3,4,5, Michele R Schaeffer1,6
1Centre for Heart Lung Innovation, The University of British Columbia and Providence Research, St Paul's Hospital, Vancouver, BC, Canada.
ERJ open research
|June 20, 2023
概括
在COVID-19之后的持续性呼吸困扰的特点是特定的感觉,如窒息和紧张. 这种呼吸困难与气体交换不良,脱水和COVID-19后焦虑和抑郁症增加有关.
科学领域:
- 肺部医学 肺部医学
- 心脏病学 心脏病学
- 精神病学是一个精神病学.
背景情况:
- 呼吸不良是COVID-19感染后的频繁和持续的症状.
- 在COVID-19后呼吸障碍的潜在机制仍然不完全理解.
- 了解这些机制对于管理长期COVID症状至关重要.
研究的目的:
- 调查COVID-19后综合征患者呼吸障碍的质量和强度.
- 评估该人口中心理健康症状的负担.
- 为了比较COVID-19后持久性呼吸不良和没有持久性呼吸不良的个体之间的运动反应.
主要方法:
- 一项涉及49名参与者的横截面研究,COVID-19疾病后4个月.
- 参与者被分为持久性呼吸障碍和没有持久性呼吸障碍的组 (修改后的医学研究理事会呼吸障碍得分≥1).
- 方法包括问卷,肺功能测试和心肺运动测试.
主要成果:
- 呼吸障碍组报告了运动呼吸障碍强度和不愉快度的增加,有窒息和紧张的特质.
- 在呼吸障碍组中观察到呼吸器低效率 (较高的VE/V'CO2最低值) 和脱水 (较低的无氧值).
- 持久性呼吸不良的个体中,焦虑,抑郁和创伤后压力症状的增加很普遍.
结论:
- 后COVID-19持续性呼吸不良与一个独特的表型有关,包括异常气体交换和脱水.
- 这种呼吸困难与心理压力增加有很大关系,包括焦虑和抑郁.
- 研究结果表明,COVID-19后呼吸不良的呼吸道,心血管和心理因素之间存在复杂的相互作用.
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