肺部超声波在COVID-19肺炎中的严重性切断点得分. 一个系统的审查和验证队列
Jaime Gil-Rodríguez1, Michel Martos-Ruiz1, Alberto Benavente-Fernández1
1Internal Medicine Unit, San Cecilio University Hospital, Avenida del Conocimiento s/n, 18016 Granada, Spain.
概括
肺部超声波得分 (LUS) 有效预测COVID-19肺炎的严重程度和患者的结果. 一个LUS>15切线点最好区分轻度和严重的疾病,帮助临床决策.
科学领域:
- 肺部病理学 肺部病理学
- 医疗成像医学成像
- 传染性疾病 传染性疾病
背景情况:
- 评估COVID-19肺炎的严重程度对于患者管理至关重要.
- 肺部超声波评分 (LUS) 是评估肺部疾病的新兴工具.
研究的目的:
- 建立肺部超声波得分 (LUS) 验证的切断点,用于分类COVID-19肺炎严重程度.
- 评估LUS和患者不良结果 (包括死亡率) 之间的关联.
主要方法:
- 对现有的COVID-19的LUS截止点进行系统审查.
- 对已确认感染SARS-CoV-2的成年患者进行前性队列研究.
- 与不良结果 (通风,ICU入院,28天死亡率) 相关的LUS分析.
主要成果:
- 在LUS>15截止点显示,与糟糕的结果最强的关联 (OR = 3.636).
- 在前性队列中,LUS与糟糕的结果 (OR = 1.303) 和28天死亡率 (OR = 1.024) 有显著的关联.
- 低于7的LUS显示出很高的灵敏度来排除不良结果,而高于20的LUS显示出很高的特异性来预测不良结果.
结论:
- 肺部超声波得分 (LUS) 是COVID-19患者不良结果和死亡率的有价值的预测指标.
- 建议的LUS截止值:轻度为≤7,中度为8-20,重度为≥20的肺炎.
- LUS>15 作为一个有效的单一切断点,用于区分轻度和重度的COVID-19肺炎.
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