由不同病原体引起的死性肺炎的临床特征
1Second Department of Infectious Disease, Kunming Children's Hospital, Kunming, Yunnan, People's Republic of China.
Infection and drug resistance
|June 20, 2023
概括
在儿童中,死性肺炎 (NP) 通常是由像Streptococcus pneumoniae.这样的细菌引起的. 包括白细胞计数和C反应蛋白在内的血液检查可以帮助识别病原体,而细菌病例更为严重.
科学领域:
- 儿童传染病 儿童传染病
- 呼吸系统药物 呼吸系统药物
- 临床微生物学 临床微生物学
背景情况:
- 死亡性肺炎 (NP) 是儿童严重的肺部感染.
- 了解致病原体及其临床特征对于有效管理至关重要.
研究的目的:
- 根据不同的致病原体,研究儿科死性肺炎的临床特征.
- 为了比较临床表现,实验室发现和由Mycoplasma pneumoniae,细菌和未识别的病原体引起的NP的结果.
主要方法:
- 在2014年1月至2022年11月期间,对282名被诊断患有NP的儿童进行了回顾性分析.
- 将其分为三组:肺炎菌种NP (MPNP),细菌NP (BNP) 和未检测到病原体NP (NNP).
- 临床数据,症状,征兆,实验室测试,成像,治疗和预后在各组之间的比较.
主要成果:
- 在34.75% (BNP) 发现了细菌病原体,22.0% (MPNP) 发现了Mycoplasma pneumoniae,50.35%没有发现病原体 (NNP).
- 常见的细菌包括肺炎性链球菌,金黄色葡萄球菌和流感性血球菌.
- 白细胞计数,C反应蛋白和白蛋白在区分MPNP和BNP方面表现出有用性,BNP病例的严重程度更高,住院时间更长.
结论:
- 细菌是儿科NP的主要原因,其中肺炎菌株,金黄色菌株和流感菌株是最常见的.
- 在NP病例中,很大一部分仍然没有发现的病原体.
- 生物标志物,如白细胞计数,C反应蛋白和白蛋白,有助于病原体的识别,指导治疗严重的细菌NP.
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